What is the Syntonic Comma?
Start with C and tune 4 perfect 5ths to E.
Start from the same C and tune 2 octaves and a pure 3rd to E.
The two Es are not the same.
A perfect 5th is 702 cents
An octave is 1200 cents and a pure 3rd is 386 cents
2808 - 2786 = 22 cents = Syntonic Comma